Virtus Genetics
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Chromosome analysis of products of conception

At least 60% of first trimester miscarriages are due to a chromosome abnormality, the majority of which are not inherited. Karyotyping the miscarriage material will be able to give an answer for the pregnancy loss in 60% of cases. Follow up genetic testing of the parents will be indicated in a small number of these cases.

Miscarriage material can be tested by conventional karyotype and if this fails microarray. Conventional karyotype helps in cases where there is a balanced structural rearrangement (which array cannot detect) as well as extra or missing genetic material.